Laurent Argaud Selected Research

(melle-4)cyclosporin

1/2017	Fast therapeutic hypothermia prevents post-cardiac arrest syndrome through cyclophilin D-mediated mitochondrial permeability transition inhibition.
1/2011	Inhibition of mitochondrial permeability transition to prevent the post-cardiac arrest syndrome: a pre-clinical study.
1/2008	Increased mitochondrial calcium coexists with decreased reperfusion injury in postconditioned (but not preconditioned) hearts.
2/2005	Specific inhibition of the mitochondrial permeability transition prevents lethal reperfusion injury.
1/2005	Postconditioning inhibits mitochondrial permeability transition.

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Laurent Argaud Research Topics

Disease

22	Critical Illness (Critically Ill) 04/2022 - 05/2015
21	COVID-19 04/2022 - 01/2020
19	Infections 01/2021 - 01/2013
14	Respiratory Insufficiency (Respiratory Failure) 07/2021 - 06/2015
14	Ischemia 01/2019 - 01/2004
12	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2022 - 01/2014
9	Reperfusion Injury 11/2022 - 01/2005
9	Sepsis (Septicemia) 03/2022 - 05/2015
9	Infarction (Infarctions) 09/2013 - 01/2004
8	Heart Arrest (Cardiac Arrest) 11/2022 - 01/2017
8	Septic Shock (Toxic Shock Syndrome) 07/2021 - 06/2016
7	Ventilator-Associated Pneumonia 10/2021 - 05/2015
7	Hypoxia (Hypoxemia) 07/2021 - 06/2015
6	Shock 04/2022 - 05/2015
6	Pneumonia (Pneumonitis) 10/2021 - 10/2011
5	Chronic Obstructive Pulmonary Disease (COPD) 01/2021 - 01/2017
4	Multiple Organ Failure (MODS) 04/2022 - 10/2014
4	Hematologic Neoplasms (Hematological Malignancy) 01/2021 - 04/2016
3	Hypothermia 11/2022 - 01/2017
3	Post-Cardiac Arrest Syndrome 01/2022 - 01/2016
3	Body Weight (Weight, Body) 10/2021 - 01/2018
3	Acidosis 01/2021 - 01/2011
3	Cross Infection (Nosocomial Infection) 01/2021 - 09/2015
3	Coma (Comas) 01/2019 - 11/2007
3	Out-of-Hospital Cardiac Arrest 01/2019 - 01/2016
3	Coinfection 01/2018 - 07/2016
2	Lymphopenia (Lymphocytopenia) 04/2022 - 01/2019
2	Disease Progression 01/2022 - 01/2007
2	Brain Injuries (Brain Injury) 01/2022 - 01/2019
2	Lung Injury 01/2022 - 10/2021
2	Inflammation (Inflammations) 01/2022 - 01/2020
2	Obesity 07/2021 - 01/2020
2	Acute Kidney Injury (Acute Renal Failure) 01/2021 - 12/2019
2	Pulmonary Aspergillosis 01/2021 - 09/2014
2	Encephalitis (Encephalitis, Rasmussen) 01/2021 - 01/2021
2	Human Influenza (Influenza) 01/2021 - 01/2018
2	Oliguria 01/2021 - 12/2019
2	Malnutrition (Nutritional Deficiencies) 06/2020 - 01/2017
2	Candidemia 04/2020 - 01/2013
2	Hyperkalemia 12/2019 - 12/2019
2	Anuria 12/2019 - 11/2007
2	Pulmonary Edema 12/2019 - 03/2018
2	Bacterial Pneumonia 01/2019 - 10/2016
2	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 01/2019 - 04/2017
2	Dyspnea (Shortness of Breath) 11/2018 - 03/2018
2	Hypercapnia 03/2018 - 06/2015
2	Status Epilepticus (Complex Partial Status Epilepticus) 01/2018 - 04/2015
2	Wounds and Injuries (Trauma) 02/2015 - 01/2011
2	Myocardial Infarction 09/2009 - 02/2005
2	Hypoventilation 06/2007 - 01/2007
1	Low Cardiac Output 04/2022
1	Bacteremia 04/2022

Drug/Important Bio-Agent (IBA)

12	Cyclosporine (Ciclosporin)FDA LinkGeneric 11/2022 - 02/2005
10	Oxygen (Dioxygen)IBA 01/2022 - 01/2011
8	Mitochondrial Permeability Transition PoreIBA 01/2019 - 01/2005
7	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 09/2015
6	salicylhydroxamic acid (SHAM)IBA 11/2022 - 01/2004
6	triphenyltetrazoliumIBA 09/2009 - 01/2004
5	Lactic Acid (Lactate)FDA LinkGeneric 04/2022 - 01/2011
5	(melle-4)cyclosporinIBA 01/2017 - 01/2005
4	Proteins (Proteins, Gene)FDA Link 11/2022 - 01/2017
4	Pharmaceutical PreparationsIBA 07/2021 - 04/2015
4	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 10/2014 - 12/2005
3	CreatinineIBA 04/2022 - 01/2011
3	Norepinephrine (Noradrenaline)FDA LinkGeneric 07/2021 - 12/2016
3	SteroidsIBA 01/2021 - 06/2017
2	TroponinIBA 11/2022 - 01/2011
2	Cyclophilins (Cyclophilin)IBA 11/2022 - 01/2017
2	HLA-DR Antigens (HLA-DR)IBA 04/2022 - 01/2016
2	Interleukin-7 (Interleukin 7)IBA 04/2022 - 03/2022
2	Biological ProductsIBA 01/2022 - 01/2021
2	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2021 - 09/2014
2	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 04/2021 - 09/2020
2	Urea (Carbamide)FDA LinkGeneric 01/2021 - 12/2019
2	Interleukin-10 (Interleukin 10)IBA 01/2020 - 07/2017
2	Messenger RNA (mRNA)IBA 07/2017 - 06/2016
2	Biomarkers (Surrogate Marker)IBA 09/2016 - 06/2016
2	Metformin (Glucophage)FDA LinkGeneric 06/2015 - 01/2011
2	Coloring Agents (Dyes)IBA 01/2008 - 01/2004
1	Peptidyl-Prolyl Isomerase FIBA 11/2022
1	Hemoglobins (Hemoglobin)IBA 04/2022

Therapy/Procedure

20	Therapeutics 01/2022 - 06/2012
18	Artificial Respiration (Mechanical Ventilation) 01/2022 - 04/2015
11	Length of Stay 01/2022 - 06/2016
11	Mechanical Ventilators (Ventilator) 01/2022 - 09/2015
9	Cannula 01/2022 - 06/2015
9	Noninvasive Ventilation 07/2021 - 01/2007
7	Critical Care (Surgical Intensive Care) 01/2022 - 11/2013
5	Resuscitation 11/2022 - 01/2011
4	Induced Hypothermia 11/2022 - 07/2015
4	Positive-Pressure Respiration (Positive End-Expiratory Pressure) 01/2021 - 06/2007
3	Continuous Renal Replacement Therapy 04/2022 - 01/2011
3	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2021 - 12/2019
2	Parenteral Nutrition 04/2022 - 01/2018
2	Enteral Nutrition (Feeding, Tube) 04/2022 - 01/2018
2	Nutritional Support (Artificial Feeding) 11/2021 - 11/2017
2	Induced Heart Arrest (Cardioplegia) 01/2020 - 10/2014
2	Contraindications 05/2019 - 01/2019
2	Percutaneous Coronary Intervention 06/2012 - 06/2011
2	Continuous Positive Airway Pressure 06/2007 - 01/2007